Mission
Therapeutic choices based on robust patient data
BOTh© analyses safety data from the patient perspective. Its aim is to assist physicians, patients, health economists and payers in choosing therapeutic agents based on meaningful clinical patient data, determining the “Price” a patient has to pay in obtaining the therapeutic benefit, providing more relavent safety data from clinical studies and an outlook on the Quality of Life.
At present, safety data are reported as an absolute list or summary, which does not optimally utilize the detailed information captured in a clinical study and other databases that collect patients and disease data.
Current methods provide a limited view of the patient experience, where the safety burden of treatment is only assessed as an overall summary over the study period.
The collective burden of therapy on the individual or treatment group is not evaluated.
The current methods do not allow the identification or differentiation of patients who experience more than one treatment-emergent adverse event (TEAE), either contemporaneously or consecutively. The presence and severity of adverse events on each day of a clinical study is not analysed.
The Burden of Therapy© provides a new insight on the patient experience, thus allowing for a better understanding of the impact of various disease states as well as therapeutic agents.
New Approach
Showing the effects on every single patient
Time
How long does the individual patient experience an adverse effect of the drug or disease and what is the severity?
The burden of therapy© combines both the incidence and severity of adverse effects on every single day.
Parallel Events
Does the patient experience more than one adverxe effect at the same time?
Current methods are focused on the single adverse effect. BOTh© reveals the combination of adverse effects, their length and grade.
Graphs & Stats
How can the therapeutic advantage of an agent be shown?
The effects and benefits are presented in intuitive graphics and statistics. This captures the benefits and adverse effects, their grade and duration for individuals and groups of patients.